Albumin, processed from human plasma, has been safely used for almost 50 years to treat critically ill patients by replacing lost fluid and maintaining adequate blood volume and pressure. Albumin has one of the longest safety records of any plasma derivative. A protein found in the body, albumin is responsible for maintenance of blood volume and transporting drugs and other molecules through the plasma. Albumin expands plasma volume and increases cardiac output. When given intravenously, albumin can draw water back into the blood (each gram of albumin draws 18 grams of water into the blood) and help restore normal hemodynamics. Albumin is used in cardiac surgery, heart valve repair and replacement, and to treat hemorrhagic shock.
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